Medical Biochemistry search menu search content Serine proteases Please navigate for more detailed information. Fibroblast activation protein (FAP) Prolylcarboxypeptidase (PRCP) Dipeptidyl peptidase 9 (DPP9) Profiling of serine protease activity Thymus specific serine protease (TSSP) Cookie prrefere…

Medical Biochemistry search menu search content Thymus specific serine protease (TSSP) The thymus specific serine protease or TSSP was identified in the late 90’s by two different laboratories1,2. It is the third member of the S28 group of serine proteases, the first member being Prolyl Carboxypep…

Medical Biochemistry search menu search content Profiling of serine protease activity Serine proteases are involved in many pathophysiological conditions throughout the human body (e.g. irritable bowel syndrome, acute lung injury, cancer, viral infections, …). As the lack of insight in the underly…

Alba Ramos Llorca onbezoldigd medewerker Onderzoek Alba Ramos Llorca Onderzoeksgroep Medicinale chemie (UAMC) Ontwerp, synthese en biochemische evaluatie van nieuwe serine protease activiteit gebaseerde probes. 01/10/2021 - 30/09/2022 Abstract Serine proteasen zijn een subgroep van de protease famil…

Jurgen Joossens domeincoördinator-diensthoofd Publicaties Jurgen Joossens The effect of serine protease inhibitors on visceral pain in different rodent models with an intestinal insult Bron Frontiers in pharmacology - ISSN 1663-9812-13 (2022) p. 1-17 Auteur(s) Hannah Ceuleers, Nikita Hanning, Miche…

Kim Van Meel doctoraatsbursaal Onderzoek Kim Van Meel Onderzoeksgroep Medische biochemie Mammalia thymus specifiek serine protease (TSSP): Ontwikkeling van hulpmiddelen om structuurgebaseerde inzichten in zijn biochemische functies te bekomen. 01/10/2024 - 30/09/2028 Abstract Thymus specifiek serine…

Koen Augustyns full professor Koen Augustyns Lectures at Scientific Symposia “Synthesis and properties of sugar modified oligonucleotides” Derde Forum der Farmaceutische Wetenschappen, Houffalize, Belgium (15-16/03/1991) “Dipeptidylpeptidase IV, a new target in the development of antidiabetic …

Alba Ramos Llorca unpaid staff Research Alba Ramos Llorca Research team Medicinal Chemistry (UAMC) Design, Synthesis and Biochemical evaluation of novel serine protease activity-based probes. 01/10/2021 - 30/09/2022 Abstract Serine proteases are a subgroup of the protease family involved in several …

Kim Van Meel doctoral scholarship holder Research Kim Van Meel Research team Medical Biochemistry Mammalian thymus specific serine protease (TSSP): Development of tools to obtain structure-based insights into its biochemical functions. 01/10/2024 - 30/09/2028 Abstract Thymus specific serine protease…

Jurgen Joossens domain coord.- head of service Publications Jurgen Joossens The effect of serine protease inhibitors on visceral pain in different rodent models with an intestinal insult Source Frontiers in pharmacology - ISSN 1663-9812-13 (2022) p. 1-17 Author(s) Hannah Ceuleers, Nikita Hanning, Mi…

Alba Ramos Llorca onbezoldigd medewerker Publicaties Alba Ramos Llorca Design, synthesis and evaluation of novel activity-based probes and inhibitors for trypsin-like serine proteases : focus on Dry eye disease (DED) and Irritable bowel syndrome (IBS) Bron Antwerp, University of Antwerp, Faculty of …

Maya Berg senior onderzoeksmanager Onderzoek Maya Berg Onderzoeksgroep Fysiofarmacologie (FYSFAR) Expertise Als wetenschappelijk onderzoeksmanager van het Infla-Med Onderzoeksexcellentie consortium (OEC) verken ik voortdurend innovatieve en multidisciplinaire onderzoekssamenwerkingen binnen en buite…

Alba Ramos Llorca unpaid staff Publications Alba Ramos Llorca Design, synthesis and evaluation of novel activity-based probes and inhibitors for trypsin-like serine proteases : focus on Dry eye disease (DED) and Irritable bowel syndrome (IBS) Source Antwerp, University of Antwerp, Faculty of Pharmac…

Maya Berg senior onderzoeksmanager Publicaties Maya Berg Chemically diverse activity-based probes with unexpected inhibitory mechanisms targeting trypsin-like serine proteases Bron Frontiers in Chemistry - ISSN 2296-2646-10 (2023) p. 1-17 Auteur(s) Alba Ramos Llorca, Lisse Decraecker, Valerie Cacheu…

Infla-Med search menu search content Opportunities New technology offer: highly selective, orally bioavailable FAP inhibitors Please see the following link/ https://medialibrary.uantwerpen.be/oldcontent/container39124/files/TTO-15-E-1706-FAP_Inhibitors.pdf Technology offer: New lead compounds for dr…

Koen Augustyns full professor Koen Augustyns PhD Students 26/09/2000 Gabrielle Thonus: Design, synthesis and biological evaluation of opioid-related prolyl peptides and pseudopeptides 10/11/2000 XueMei Zhang: Design, synthesis and evaluation of dipeptidyl peptidase IV (DPP IV) inhibitors 25/06/2002 …

Maya Berg senior research manager Publications Maya Berg Chemically diverse activity-based probes with unexpected inhibitory mechanisms targeting trypsin-like serine proteases Source Frontiers in Chemistry - ISSN 2296-2646-10 (2023) p. 1-17 Author(s) Alba Ramos Llorca, Lisse Decraecker, Valerie Cach…

Medical Biochemistry search menu search content Dipeptidyl peptidase 9 (DPP9) DPP9 in a nutshell Dipeptidyl peptidase 9 (DPP9), an intracellular serine protease, has recently been identified as a key player in pro-inflammatory cell death and regulation of the innate immune response. Similar to its c…

Informatie voor bedrijven zoeken menu zoek inhoud Life sciences Licentieaanbod Serine protease inhibitors to treat visceral pain The University of Antwerp has developed an in vivo proof of concept with serine protease inhibitors in a validated gastrointestinal IBS model for visceral pain. Pharmaceut…

Veerle Matheeussen associate professor - unpaid guest prof. Research Veerle Matheeussen Research team Medical Biochemistry Expertise Evaluation of (molecular) diagnostic assays for detection of respiratory viruses and bacteria Surveillance of vancomycin and linezolid resistance in Enterococci Detect…

Info for companies search menu search content Life sciences License offers Serine protease inhibitors to treat visceral pain The University of Antwerp has developed an in vivo proof of concept with serine protease inhibitors in a validated gastrointestinal IBS model for visceral pain. Pharmaceutical…

Anne-Marie Lambeir emeritus occasionele opdracht Onderzoek Anne-Marie Lambeir Onderzoeksgroep Expertise - Prolyloligopeptidase in het centraal zenuwstelsel en prolyloligopeptidase remmers: nieuw strategiën voor de behandeling van neurodegeneratieve ziekten en Carboxypeptidase M: substraten en inter…

Margarida Florindo Espadinha senior researcher Research Margarida Florindo Espadinha Research team Medicinal Chemistry (UAMC) DPP9 degradation-induced pyroptosis for treatment of acute myeloid leukemia (DPP9-TACDrug). 01/04/2023 - 31/03/2025 Abstract Dipeptidyl-peptidase 9 (DPP9) is a proline-select…

Koen Augustyns gewoon hoogleraar Onderzoek Koen Augustyns Onderzoeksgroep Medicinale chemie (UAMC) Expertise Koen Augustyns (°13/09/1965) behaalde een Master en PhD in de Farmaceutische Wetenschappen aan de KU Leuven, België in 1988 en 1992 respectievelijk. Na postdoctorale verblijven aan de Unive…

Medical Biochemistry search menu search content Research topics The basic research interest is always to find novel targets and unravel the structure-function relationship of target proteins within a given pathophysiological context. The current research topics are: Serine proteases Carboxypeptidase…