84 results found
Serine proteases | Medical Biochemistry | University of Antwerp
Medical Biochemistry search menu search content Serine proteases Please navigate for more detailed information. Fibroblast activation protein (FAP) Prolylcarboxypeptidase (PRCP) Dipeptidyl peptidase 9 (DPP9) Profiling of serine protease activity Thymus specific serine protease (TSSP) Cookie prrefere…
Profiling of serine protease activity | Medical Biochemistry | University of Antwerp
Medical Biochemistry search menu search content Profiling of serine protease activity Serine proteases are involved in many pathophysiological conditions throughout the human body (e.g. irritable bowel syndrome, acute lung injury, cancer, viral infections, …). As the lack of insight in the underly…
Thymus specific serine protease (TSSP) | Medical Biochemistry | University of Antwerp
Medical Biochemistry search menu search content Thymus specific serine protease (TSSP) The thymus specific serine protease or TSSP was identified in the late 90’s by two different laboratories1,2. It is the third member of the S28 group of serine proteases, the first member being Prolyl Carboxypep…
Life sciences | Info for companies | University of Antwerp
Info for companies search menu search content Life sciences License offers Serine protease inhibitors to treat visceral pain The University of Antwerp has developed an in vivo proof of concept with serine protease inhibitors in a validated gastrointestinal IBS model for visceral pain. Pharmaceutical…
Koen Augustyns | Koen Augustyns | University of Antwerp
Koen Augustyns full professor Koen Augustyns Lectures at Scientific Symposia “Synthesis and properties of sugar modified oligonucleotides” Derde Forum der Farmaceutische Wetenschappen, Houffalize, Belgium (15-16/03/1991) “Dipeptidylpeptidase IV, a new target in the development of antidiabetic …
Research Kim Van Meel | Kim Van Meel | University of Antwerp
Kim Van Meel doctoral scholarship holder Research Kim Van Meel Research team Medical Biochemistry Mammalian thymus specific serine protease (TSSP): Development of tools to obtain structure-based insights into its biochemical functions. 01/10/2024 - 30/09/2028 Abstract Thymus specific serine protease…
ESR1 Alba Ramos Llorca | Integrated Training in Dry Eye Disease Drug Development | University of Antwerp
Integrated Training in Dry Eye Disease Drug Development search menu search content ESR1 Alba Ramos Llorca Research project: Design, Synthesis and Biochemical evaluation of novel serine protease inhibitors. Host organisation: University of Antwerp (UA), Belgium Supervisor: Prof. Dr. Koen AUGUSTYNS Br…
Opportunities | Infla-Med | University of Antwerp
Infla-Med search menu search content Opportunities New technology offer: highly selective, orally bioavailable FAP inhibitors Please see the following link/ https://medialibrary.uantwerpen.be/oldcontent/container39124/files/TTO-15-E-1706-FAP_Inhibitors.pdf Technology offer: New lead compounds for dr…
#ProjectOverview | Integrated Training in Dry Eye Disease Drug Development | University of Antwerp
Integrated Training in Dry Eye Disease Drug Development search menu search content #ProjectOverview ESR1: Design, Synthesis and Biochemical evaluation of novel serine protease inhibitors. University of Antwerp ESR2: Design, Synthesis and Biochemical evaluation of novel RIPK1 inhibitors. University o…
Research Projects | Integrated Training in Dry Eye Disease Drug Development | University of Antwerp
Integrated Training in Dry Eye Disease Drug Development search menu search content Research Projects ESR1: Design, Synthesis and Biochemical evaluation of novel serine protease inhibitors. University of Antwerp ESR2: Design, Synthesis and Biochemical evaluation of novel RIPK1 inhibitors. University …
Koen Augustyns | Koen Augustyns | University of Antwerp
Koen Augustyns full professor Koen Augustyns PhD Students 26/09/2000 Gabrielle Thonus: Design, synthesis and biological evaluation of opioid-related prolyl peptides and pseudopeptides 10/11/2000 XueMei Zhang: Design, synthesis and evaluation of dipeptidyl peptidase IV (DPP IV) inhibitors 25/06/2002 …
Doctoral Theses | Integrated Training in Dry Eye Disease Drug Development | University of Antwerp
Integrated Training in Dry Eye Disease Drug Development search menu search content Doctoral Theses January 15th, 2024 Development of New Carriers to Improve the Bioavailability of Natural Compounds for the Treatment of Ocular Surface Disorders Author: Luna Krstić, University of Valladolid Superviso…
Dipeptidyl peptidase 9 (DPP9) | Medical Biochemistry | University of Antwerp
Medical Biochemistry search menu search content Dipeptidyl peptidase 9 (DPP9) DPP9 in a nutshell Dipeptidyl peptidase 9 (DPP9), an intracellular serine protease, has recently been identified as a key player in pro-inflammatory cell death and regulation of the innate immune response. Similar to its c…
SYMPOSIUM 'DRY EYE DISEASE' | Integrated Training in Dry Eye Disease Drug Development | University of Antwerp
Integrated Training in Dry Eye Disease Drug Development search menu search content SYMPOSIUM 'DRY EYE DISEASE' LIVE-STREAMING EVENT | 2 December 2021 DOWNLOAD PROGRAMME Opening & Welcome Note | Christophe Baudouin, MD, PhD. President of the European Dry Eye Society - EuDES. Professor of Ophthalmolog…
Life sciences | Info for companies | University of Antwerp
Info for companies search menu search content Life sciences License offers New lead compounds for dry eye disease and validated dry eye rat model The University of Antwerp has developed a new lead compound and a validated rat model for dry eye disease (DED). Pharmaceutical companies looking for a pr…
Technology offers | Integrated Training in Dry Eye Disease Drug Development | University of Antwerp
Integrated Training in Dry Eye Disease Drug Development search menu search content Technology offers New lead compounds for dry eye disease and validated dry eye disease rat model Please also see the publication A novel serine protease inhibitor as potential treatment for dry eye syndrome and ocular…
Research topics | Medical Biochemistry | University of Antwerp
Medical Biochemistry search menu search content Research topics The basic research interest is always to find novel targets and unravel the structure-function relationship of target proteins within a given pathophysiological context. The current research topics are: Serine proteases Carboxypeptidase…
Research Ingrid De Meester | Ingrid De Meester | University of Antwerp
Ingrid De Meester full professor Research Ingrid De Meester Research team Medical Biochemistry Expertise The overall focus of the research group is the study of Structure-function relationship of proteins among which enzymes, by using a combination of protein chemistry, biophysical techniques, and s…
Publications | Integrated Training in Dry Eye Disease Drug Development | University of Antwerp
Integrated Training in Dry Eye Disease Drug Development search menu search content Publications 2024 Greta Klejborowska, Camilla Scarpellini, Caroline Lanthier, and Koen Augustyns. Recent advances in the development of synthetic ferroptosis inhibitors. 2024 Medicinal Chemistry Reviews, Chapter 14, p…
Poster and oral presentations | Medical Biochemistry | University of Antwerp
Medical Biochemistry search menu search content Poster and oral presentations Joint Parasitology Spring Meeting | March 11-14, 2025 | Würzburg, Germany L. De Vocht, G. Caljon, Y. G.-J. Sterckx. Identification of potent single-domain antibodies against the malaria sporozoite through a synthetic sing…
Research | Integrated Training in Dry Eye Disease Drug Development | University of Antwerp
Integrated Training in Dry Eye Disease Drug Development search menu search content Research The major research objective is to accelerate new therapy - and biomarker development by creating a multidisciplinary European research and training network around DED research. IT-DED3 constitutes a unique p…
Research Veerle Matheeussen | Veerle Matheeussen | University of Antwerp
Veerle Matheeussen associate professor Research Veerle Matheeussen Research team Medical Biochemistry Expertise Evaluation of (molecular) diagnostic assays for detection of respiratory viruses and bacteria Surveillance of vancomycin and linezolid resistance in Enterococci Detection of virulence and …
DC1 Nikita Shikut | OncoProTools | University of Antwerp
OncoProTools search menu search content DC1 Nikita Shikut Design and discovery of novel GrnzB ligands and evaluation as diagnostics tools in CAR T cell therapy assessment Organisation: University of Antwerp, Belgium Supervisor: Prof. Dr. Pieter Van der Veken Co-supervisors: Prof. Dr. Filipe Elvas an…
Publications Michaela Prothiwa | Michaela Prothiwa | University of Antwerp
Michaela Prothiwa TT. asst. research professor Publications Michaela Prothiwa Synthesis and application of activity-based probes for serine proteases Source Methods in molecular biology - ISSN 1064-3745-2921 (2025) p. 217-230 Author(s) Alba Ramos Llorca, Valeria Parravicini, Koen Augustyns, Michaela…
Research Anne-Marie Lambeir | Anne-Marie Lambeir | University of Antwerp
Anne-Marie Lambeir emeritus occasional assignment Research Anne-Marie Lambeir Research team Expertise - Prolyl oligopeptidase in the central nervous system and prolyl oligopeptidase inhibitors: new therapeutic strategies in neurodegenerative disease and Carboxypeptidase M: substrates and interaction…