Plasma medicine

Effect of plasma-induced oxidation on NK cell immune checkpoint ligands: A computational-experimental approach.
P. Heirman, H. Verswyvel, M. Bauwens, M. Yusupov, J. De Waele, A. Lin, E. Smits and A. Bogaerts
Redox Biology, 77, 103381 (2024)​

Characterization of regulated cancer cell death pathways induced by the different modalities of non-thermal plasma treatment.
E. Biscop, J. Baroen, J. De Backer, W. Vanden Berghe, E. Smits, A. Bogaerts and A. Lin
​Cell Death Discov., 10, 416 (2024) and supplementary material​

Injectable plasma-treated alginate hydrogel for oxidative stress delivery to induce immunogenic cell death in osteosarcoma.

M. Živanic, A. Espona-Noguera, H. Verswyvel, E. Smits, A. Bogaerts, A. Lin and C. Canal

Adv. Functional Mater., 2023, 231205 (2023)​

Inactivation of SARS-CoV‑2 and other enveloped and non-enveloped viruses with non-thermal plasma for hospital disinfection.

M. Sahun, A. Privat-Maldonado, A. Lin, N. De Roeck, L. Van der Heyden, M. Hillen, J. Michiels, G. Steenackers, E. Smits, K.K. Ariën, P.G. Jorens, P. Delputte, and A. Bogaerts

ACS Sustain. Chem. Eng., 11, 5206-5215 (2023)​

Acquired non-thermal plasma resistance mediates a shift towards aerobic glycolysis and ferroptotic cell death in melanoma.

A. Lin, M. Sahun, E. Biscop, H. Verswyvel, J. De Waele, J. De Backer, C. Theys, B. Cuypers, K. Laukens, W. Vanden Berghe, E. Smits and A. Bogaerts

​Drug Resi. Ups., 67, 100914 (2023) and supporting information​

The pro- and anti-tumoral properties of gap junctions in cancer and their role in therapeutic strategies.
M.C. Oliveira, H. Verswyvel, E. Smits, R.M. Cordeiro, A. Bogaerts and A. Lin
Redox Biology, 57, 102503 (2022)​

The effect of local non-thermal plasma therapy on the cancerimmunity cycle in a melanoma mouse model.
A. Lin, J. De Backer, D. Quatannens, B. Cuypers, H. Verswyvel, E. Cardenas De La Hoz, B. Ribbens, V. Siozopoulou, J. Van Audenaerde, E. Marcq, F. Lardon, K. Laukens, S. Vanlanduit, E. Smits, A. Bogaerts
Bioeng Transl Med., 7 e10314 - (2022) and its supporting information​

Oxidative damage to hyaluronan–CD44 interactions as an underlying mechanism of action of oxidative stress-inducing cancer therapy.

M. Yusupov, A. Privat-Maldonado, R.M. Cordeiro, H. Verswyvel, P. Shaw, J. Razzokov, E. Smits and A. Bogaerts

Redox Biology, 43, 101968 (2021)​

Oxidation of innate immune checkpoint CD47 on cancer cells with non-thermal plasma.

A. Lin, J. Razzokov, H. Verswyvel, A. Privat-Maldonado, J. De Backer, M. Yusupov, E. Cardenas De La Hoz, P. Ponsaerts, E. Smits and A. Bogaerts

Cancers, 13, 579 (2021)​

Critical evaluation of the interaction of reactive oxygen and nitrogen species with blood to inform the clinical translation of nonthermal plasma therapy.
A. Lin, E. Biscop, C. Breen, S.J. Butler, E. Smits and A. Bogaerts
Ox. Med. Cell. Long., 2020, 9750206 (2020)​

Cold atmospheric plasma treatment for pancreatic cancer - The importance of pancreatic stellate cells.
R. Verloy, A. Privat-Maldonado, E. Smits and A. Bogaerts
Cancers, 12, 2782 (2020)​

Influence of cell type and culture medium on determining cancer selectivity of cold atmospheric plasma treatment.
E. Biscop, A. Lin, W. Van Boxem, J. Van Loenhout, J. De Backer, C. Deben, S. Dewilde, E. Smits, and A. Bogaerts
Cancers,11, 1287 (2019)

Non-thermal plasma as a unique delivery system of short-Lived reactive oxygen and nitrogen species for immunogenic cell death in melanoma cells.
A. Lin,Y. Gorbanev, J. De Backer, J. Van Loenhout, W. Van Boxem, F. Lemière, P. Cos, S. Dewilde, E, Smits and A. Bogaerts
Adv. Sci., 2019, 1802062 (2019)

Reduction of human glioblastoma spheroids using cold atmospheric plasma: The combined effect of short- and long-lived reactive species.
A. Privat-Maldonado, Y. Gorbanev, S. Dewilde, E. Smits and A. Bogaerts
Cancers, 10, 394 (2018)
 

Transport and accumulation of plasma generated species in aqueous solution.
C.C.W. Verlackt, W. Van Boxem and A. Bogaerts
Phys. Chem. Chem. Phys., 20, 6845-6859 (2018)

Anti-cancer capacity of plasma-treated PBS: effect of chemical composition on cancer cell cytotoxicity.
W. Van Boxem, J. Van der Paal, Y. Gorbanev, S. Vanuytsel, E. Smits, S. Dewilde and A. Bogaerts
Scientif. Rep., 7, 16478 (2017)  including its supplementary information.

Synergistic effect of electric field and lipid oxidation on the permeability of cell membranes.
M. Yusupov, J. Van der Paal, E.C. Neyts and A. Bogaerts
Biochim. Biophys. Acta, 1861, 839-847 (2017)

Effect of lipid peroxidation on membrane permeability of cancer and normal cells subjected to oxidative stress.
J. Van der Paal, E.C. Neyts, C.C.W. Verlackt and A. Bogaerts
Chem. Sci., 7, 489-498 (2016)

Multi-level molecular modelling for plasma medicine.
A. Bogaerts, N. Khosravian, J. Van der Paal, C.C.W. Verlackt, M. Yusupov, B. Kamaraj and E.C. Neyts
J. Phys. D: Appl. Phys., 49, 054002 (2016)

Reaction pathways of biomedically active species in an Ar plasma jet.
W. Van Gaens and A. Bogaerts
Plasma Sources Sci. Technol., 23, 035015 (2014)
(Selected by the editors of Plasma Sources Science and Technology as one of the “Highlights of 2014")

Atomic-scale simulations of reactive oxygen plasma species interacting with bacterial cell walls.
M. Yusupov, E.C. Neyts, U. Khalilov, R. Snoeckx, A.C.T. van Duin and A. Bogaerts
New J. Phys., 14, 093043 (2012)(Selected as one of the "IOPselect” publications)