Medicinal Chemistry search menu search content Inflammation Inflammatory caspases Current work on the inflammatory caspases (mainly caspase-1) was initiated as an application of the MSAS approach discussed below. This fragment-based methodology identified several carboxylate isostere-containing buil…

Gert Verpooten emeritus occasionele opdracht Onderzoek Gert Verpooten Onderzoeksgroep Leerstoel Nefrologie. 20/12/2011 - 19/12/2012 Abstract Dit project kadert in een onderzoeksopdracht tussen enerzijds UA en anderzijds een privé-instelling. UA levert aan de privé-instelling de onderzoeksresultate…

Gert Verpooten emeritus occasional assignment Research Gert Verpooten Research team Scientific Chair Nephrology. 20/12/2011 - 19/12/2012 Abstract This project represents a formal research agreement between UA and on the other hand a private institution. UA provides the private institution research r…

Koen Augustyns full professor Koen Augustyns PhD Students 26/09/2000 Gabrielle Thonus: Design, synthesis and biological evaluation of opioid-related prolyl peptides and pseudopeptides 10/11/2000 XueMei Zhang: Design, synthesis and evaluation of dipeptidyl peptidase IV (DPP IV) inhibitors 25/06/2002 …

Tony Van Havenbergh onbezoldigd medewerker Publicaties Tony Van Havenbergh Complete transection of optic nerve after endovascular coiling of a large ophthalmic artery aneurysm Bron World neurosurgery - ISSN 1878-8750-132 (2019) p. 81-86 Auteur(s) Barbara Verbraeken, Salah-Eddine Achahbar, Niels Kame…

Integrated Personalized and Precision Oncology Network search menu search content Novel combination strategies with immunotherapy IPPON preclinically and clinically investigates combining immune stimulation with immune checkpoint blockade to further boost the antitumor immunity by acting on differen…

Lidia Carotenuto postdoctoraal bursaal Publicaties Lidia Carotenuto Kv7 channel activation reduces brain endothelial cell permeability and prevents kainic acid-induced blood-brain barrier damage Bron American journal of physiology : cell physiology - ISSN 0363-6143-326:3 (2024) p. C893-C904 Auteur(s…

Tony Van Havenbergh unpaid staff Publications Tony Van Havenbergh Complete transection of optic nerve after endovascular coiling of a large ophthalmic artery aneurysm Source World neurosurgery - ISSN 1878-8750-132 (2019) p. 81-86 Author(s) Barbara Verbraeken, Salah-Eddine Achahbar, Niels Kamerling, …

Medical Biochemistry search menu search content Drug screening Researchers of the Medical Biochemistry group develop purification methods for the enzymes they study, from natural sources as well as recombinant organisms. They develop assays that can be used to assess activity in complex biological s…

Medicinal Chemistry search menu search content Technology development Activity-based probes in bioimaging We were the first to report on small, irreversible uPA inhibitors with nanomolar potency and a surprising selectivity against highly related enzymes such as tPA, plasmin, thrombin and fXa. Selec…

Jurgen Joossens domeincoördinator-diensthoofd Onderzoek Jurgen Joossens Onderzoeksgroep IOF Alliance Valorisatiemanager UAntwerpen - UZA 07/11/2022 - 31/12/2026 Abstract In de levenswetenschappen werken meerdere AUHA onderzoeksgroepen op regelmatige basis samen met het bedrijfsleven. Een aantal van…

Tim Van den Wyngaert hoofddocent Onderzoek Tim Van den Wyngaert Onderzoeksgroep Moleculaire Beeldvorming en Radiologie (MIRA) Optimaliseren van theranostische radiofarmaca voor gepersonaliseerde geneeskunde. 01/11/2024 - 31/10/2026 Abstract Kanker-geassocieerde fibroblasten (CAFs) vertegenwoordigen …

Tim Van den Wyngaert associate professor Research Tim Van den Wyngaert Research team Molecular Imaging and Radiology (MIRA) Optimized theranostic tools for personalized medicine. 01/11/2024 - 31/10/2026 Abstract Cancer-associated fibroblasts (CAFs) are a group of tumor stromal cells typically associ…

Koen Augustyns gewoon hoogleraar Onderzoek Koen Augustyns Onderzoeksgroep Medicinale chemie (UAMC) Expertise Koen Augustyns (°13/09/1965) behaalde een Master en PhD in de Farmaceutische Wetenschappen aan de KU Leuven, België in 1988 en 1992 respectievelijk. Na postdoctorale verblijven aan de Unive…

Hans De Winter professor Research Hans De Winter Research team Medicinal Chemistry (UAMC) Expertise Computational chemistry Chemoinformatics Molecular modeling Computer-aided drug design Protein structure-based drug design Quantitative structure-activity relationships (QSAR) CalcUA 01/01/2022 - 31/1…

Jurgen Joossens domain coord.- head of service Research Jurgen Joossens Research team IOF Alliance Valorisation Manager UAntwerpen - UZA 07/11/2022 - 31/12/2026 Abstract In the life sciences, several AUHA research groups collaborate with the business community on a regular basis. Some of the profess…

Hans De Winter hoogleraar Onderzoek Hans De Winter Onderzoeksgroep Medicinale chemie (UAMC) Expertise Computationele Chemie Chemoinformatica Moleculaire modelering Computer-gedreven geneesmiddelenontwikkeling Eiwitstructuur-gedreven geneesmiddelenontwikkeling Structure-activiteitsrelaties CalcUA. 01…

Laurie Freire Boullosa unpaid staff Research Laurie Freire Boullosa Research team Center for Oncological Research (CORE) Rationally designed drug combination screen with the drug repurposing candidate Auranofin using patientderived NSCLC and PDAC 3D organoids. 01/11/2022 - 30/04/2023 Abstract Non-sm…

Koen Augustyns full professor Research Koen Augustyns Research team Medicinal Chemistry (UAMC) Expertise Koen Augustyns (°13/09/1965) obtained his Master and PhD in Pharmaceutical Sciences at the KU Leuven, Belgium in 1988 and 1992 respectively. After postdoctoral stays at the University of Antwerp…

Medicinal Chemistry search menu search content Projects Ongoing projects Development of chemical tools for deciphering the virulent roles of Streptococcus pneumoniae HtrA protease. 01/10/2024 - 30/09/2027 Abstract Streptococcus pneumoniae (SP) is a leading cause of community-acquired pneumonia, with…

Dirk Hendriks emeritus occasional assignment Research Dirk Hendriks Research team Expertise Biological markers of affective disorders. Analysis of drugs and metabolites concentrations in biological matrices (serum, plasma, urine). Support maintenance scientific equipment (Medical Biochemistry). 01/0…

Pieter Van Der Veken full professor Research Pieter Van Der Veken Research team Medicinal Chemistry (UAMC) Expertise Medicinal chemistry & drug discovery, pharmaceutical chemistry, organic chemistry & organic synthesis Bench-to-bedside research into the role of regulated cell death and barrier dysfu…

Pieter Van Der Veken gewoon hoogleraar Onderzoek Pieter Van Der Veken Onderzoeksgroep Medicinale chemie (UAMC) Expertise Medicinale chemie & drug discovery, farmaceutische chemie, organische chemie & organische synthese Bench-to-bedside onderzoek naar de rol van gereguleerde celdood en barrièredysf…

Applied Engineering PhD defences in 2022 Attend a PhD defence or find the archive of concluded doctoral research PhD defences in 2022 Attend a PhD defence or find the archive of concluded doctoral research Towards an enhanced understanding of the oxidative ageing mechanisms in bitumen (15/12/2022) G…

Toegepaste Ingenieurswetenschappen 2022 Woon een doctoraat bij of raadpleeg de voorbije verdedigingen 2022 Woon een doctoraat bij of raadpleeg de voorbije verdedigingen Towards an enhanced understanding of the oxidative ageing mechanisms in bitumen (15/12/2022) Georgios Pipintakos donderdag 15 decem…